Understanding of Obesity

Neurobiological Understanding of Obesity: New Treatment Guidelines and Patient-Centered Approach

CME Information

Learning Objectives

After participating in this educational activity, participants should be better able to:

  1. Screen for risk factors of obesity and diagnose obesity as a disease early in its evolution
  2. Prescribe pharmacological intervention for obesity based on the neurobiology and pathophysiology of the disease following the National Heart, Lung and Blood Institute (NHLBI) guidelines
  3. Describe the safety and efficacy studies of various agents and create awareness of post marketing and long term pharmacovigilance studies to assess long term risks
  4. Focus on obesity as disease and provide communication strategies to build ongoing collaborative relationships with obese patients


Obesity has reached epidemic proportions for both children and adults and has become a major public health problem. Two-thirds of adults are overweight; one-third of them are obese. Obesity is associated with significant health risks and comorbidities including diabetes, metabolic syndrome, cancer, heart disease, depression, sleep apnea, osteoarthritis, and others.

Lifestyle interventions focused on diet, physical activity, and behavioral therapy are essential components to treating obesity and should be incorporated throughout the continuum of care. Some patients will successfully achieve weight loss with these efforts alone; however it is well documented that long-term weight loss and maintenance is difficult to achieve. When “first-line” interventions alone have not succeeded, the National Heart Lung and Blood Institute (NHLBI) guidelines recommend pharmacological intervention as an option.

This CME article will present the clinical realities of obesity encouraging an open provider/patient relationship that enhances care, allowing for discussions on goals, adherence, barriers, and expectations.


This activity has expired and is no longer available for CME; however, we hope you still enjoy the education.

Published on December 30, 2014