Hypogonadism in Men
Practical Primary Care Strategies for Diagnosing and Managing Hypogonadism in Men – Best Practices to Improve Patient Outcomes
Hypogonadism is characterized by a deficiency or decreased level of endogenous testosterone. This past decade has witnessed a rapidly growing awareness of the important role of testosterone. Testosterone deficiency is associated with a well-documented increase in risk of mortality and detrimental effects on quality of life: loss of energy and libido, erectile dysfunction (ED), joint pain and stiffness, memory impairment, irritability, and depression. In spite of this, hypogonadism remains an underdiagnosed syndrome that, with its links to age, obesity, type 2 diabetes mellitus (T2DM), and metabolic syndromes, is becoming increasingly relevant. Furthermore, less than 10% of affected individuals with hypogonadism have been shown to receive testosterone supplement therapy. It will be increasingly important for clinicians to understand potential differences among available supplement therapies, such as efficacy, convenience, uniformity of dose, and the flexibility of dose modifications that influence adherence.
After completing this activity, the participant should be better able to:
- Identify potential hypogonadism in men based on clinical presentation
- Utilize appropriate screening measures and criteria to diagnose hypogonadism in men
- Assess available testosterone supplement modalities with respect to their convenience, pharmacokinetic profile, patient preference, safety, and efficacy
- Prescribe guideline-recommended testosterone replacement therapy based on convenience, pharmacokinetic profile, patient preference, safety, and efficacy considerations
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Published August 5, 2014