Tranexamic Acid for the Treatment of Heavy Menstrual Bleeding: Efficacy and Safety
Even though tranexamic acid is used frequently worldwide, clinicians in the US apparently have been hesitant to prescribe it for heavy menstrual bleeding (HMB) due to concerns over the incidence of thrombotic events associated with its use. A recent meta-analysis that focuses on the efficacy and safety of tranexamic acid in the treatment of idiopathic HMB concluded that 3.9-4 g/day for 4-5 days is an effective treatment for HMB. The authors stated, “Tranexamic acid is well tolerated and has a favorable safety profile. Adverse effects are few and they are mainly mild to moderate.” It also costs less than surgery with fewer side effects.
For CME on HMB, www.primaryissues.org/?s=heavy+menstrual+bleeding&x=2&y=9
Have you prescribed tranexamic acid for HMB?
Do you find it efficacious for HMB?
Do you have concerns over prescribing tranexamic acid for HMB? If so, please state one of them.